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Topics - mora

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General Discussion / IC from PSAM
« on: May 24, 2019, 04:36:26 pm »
What does the information content (IC) from logos built from a PSAM matrix mean? how does this differ from IC inferred from a classic PSSM/PWM matrix?

Also, is there any information about how LogoGenerator calculate the IC in bits from the values in the PSAM? I assume it has to be very different from how it is calculated according to classic PWM right? (see link)


Is topology equal to kmers size of the binding site? what if I want to explore kmer sizes > 8?

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Created and maintained by Dr. Xiang-Jun Lu [律祥俊]. See also and