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TB binding site binding affinity compared to mutant
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amanzour:
Hi
How can I calculate the change between binding affinity of a transcription factor binding site and its corresponding mutated version of it. TF protein is known.
Would it be possible to do it web based?
Basically inputting: Sequence, mutant, TF and outputting change in TF binding affinity
Thank you so much beforehand
xiangjun:
Thanks for using the REDUCE Suite and for posting your questions on the Forum.
Unfortunately, I do not know how to calculate the change in binding affinity between wild and mutated sites of a TF binding site. Currently, the REDUCE Suite is command-line based only, no web interface to it.
Best regards,
Xiang-Jun
amanzour:
Thank you Lu.
How can I install Reducesuite?
are there a series of command line for linux?
Thank you
Amir
xiangjun:
Did you read the Documentation Section?
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