General Category > General Discussion

TB binding site binding affinity compared to mutant

(1/1)

amanzour:
Hi
How can I calculate the change between binding affinity of a transcription factor binding site and its corresponding mutated version of it. TF protein is known.
Would it be possible to do it web based?
Basically inputting: Sequence, mutant, TF and outputting change in TF binding affinity

Thank you so much beforehand

xiangjun:
Thanks for using the REDUCE Suite and for posting your questions on the Forum.

Unfortunately, I do not know how to calculate the change in binding affinity between wild and mutated sites of a TF binding site. Currently, the REDUCE Suite is command-line based only, no web interface to it.

Best regards,

Xiang-Jun

amanzour:
Thank you Lu.

How can I install Reducesuite?
are there a series of command line for linux?
Thank you
Amir

xiangjun:
Did you read the Documentation Section?

Navigation

[0] Message Index